Pharmacokinetics of diazepam in epileptic patients and normal volunteers following intravenous administration.
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منابع مشابه
Pharmacokinetics of Cefepime Following Intravenous and Intramuscular Administration in Sheep
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متن کاملIntravenous administration of diazepam in patients
was 17-9 + 1-4 mg (M ± SEM) compared with 27 ± 5-4 mg in controls (p < 0 01). Dose correlated significantly with serum albumin (p < 0-05). Baseline mean dominant frequency (MDF) and slow wave index (SWI) significantly correlated with albumin (p < 0 01). After diazepam, the MDF decreased and SWI increased. The change was greatest at the time of maximal clinical response. It was greater in liver ...
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Pharmacokinetics of ceftriaxone was studied in buffalo calves (Bubalus bubalis) after single intravenousand intramuscular administration of 10 mg/kg body weight. The drug concentrations in plasma samples weremeasured by high performance liquid chromatography with UV detection. Following intravenousadministration, the drug was rapidly distributed (Cpo: 106.5 ± 9.64 μg/ml; t1/2α: 0.09 ± 0.01 h; V...
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Pharmacokinetics of cefepime was studied after single dose intravenous administration at the dose rate of 5 mg/kg body weight in calves. Blood samples were collected from the jugular vein at predetermined time intervals before and after drug administration. Serum was harvested and analysed for cefepime concentration by reverse-phase high performance liquid chromatography. Following intravenous...
متن کاملThe Pharmacokinetics of Rafoxanide following Single Dose Intravenous and Oral Administration in Goats
The study was conducted to determine the plasma concentrations and pharmacokinetic parameters of rafoxanide after a single intravenous (10 mg/kg) and oral (22.5 mg/kg) administrations in black Bengal female goats. Maximum (87.63 11.71 mg/mL) and minimum (1.8 0.24 mg/mL) plasma concentrations of rafoxanide were recorded at 0.08 and 12 h respectively after i.v. administration. The elimination h...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1981
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1981.tb01317.x